Central nervous system–directed prophylactic chemotherapy increases survival in childhood leukemia, but possible late neurocognitive sequelae remain a concern. We compared intellectual performance (WAIS IV), memory (AVLT), and executive functioning (ANT) between adult leukemia survivors (n = 31) and control individuals (n = 35). In survivors, cerebrospinal fluid (CSF) levels of phosphorylated Tau (p-Tau) during treatment and total intrathecal methotrexate dose correlated with adult intellectual performance (Pearson’s and Spearman’s coefficients, respectively).
Welcome to the Northern Ireland Cancer Network
Key hospital contacts
Belfast Health and Social Care Trust
All Royal Hospitals: (028) 9024 0503
Belfast City Hospital: (028) 9032 9241
Northern Health and Social Care Trust
Telephone: (028) 9442 4000
South Eastern Health and Social Care Trust
Ulster Hospital: (028) 9048 4511
Southern Health and Social Care Trust
Telephone: (028) 3833 4444
Western Health and Social Care Trust
Telephone: (028) 7134 5171
The Northern Ireland Cancer Network is a partnership of HSCNI organisations, academic, charity, cancer specialists and service users working in collaboration to deliver safe and effective care, improve cancer clinical outcomes and enhance patients and carers experience and quality of life.
Who are we & what do we do?
The Northern Ireland Cancer Network was formed in 2004 as Northern Ireland’s first Regional Clinical Network and links together the organisations that provide care for people with cancer across the 5 Health & Social care trusts in Northern Ireland. The Network is part of the Health and Social Care Board.
We do not actively deliver patient care, but work closely with service users, health professionals and managers to improve cancer services and to implement national and local NHS strategies.
- support our members in the delivery of services that are evidence based
- ensure equity of access and uniform quality of services for the population of Northern Ireland, and
- work across organisational boundaries following the patient pathway.