Cancer therapies that are gone with the Wnt

21 Sep 2015
Science AAAS Journal

Cancer therapies that are gone with the Wnt

The isolation and molecular characterization of circulating tumor cells (CTCs) to guide cancer therapy is a particularly attractive approach for men with metastatic prostate cancer where the primary tumor may have been removed years earlier and the only indication of disease progression may be a rising amount of prostate-specific antigen (PSA) in the blood and a worsening bone scan (the skeleton is commonly the first area of metastasis for this cancer). Consequently, numerous technologies to capture, isolate, and study prostate cancer CTCs have been developed, each with its own limitations.